For adults over 35, targeted supplementation can play a crucial role in supporting cellular health and combating the natural decline associated with aging. While a balanced diet and active lifestyle are foundational, certain compounds have shown promise in scientific studies for extending healthspan.
Nicotinamide Mononucleotide (NMN)
NMN is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a vital coenzyme found in every cell of your body. NAD+ plays a critical role in energy metabolism, DNA repair, and gene expression. As we age, NAD+ levels naturally decline, contributing to various age-related health issues.
- What it does: Boosts NAD+ levels, supporting cellular energy production and repair processes.
- Science Says: Early human trials show promising results for improving metabolic health and reducing biological age markers.
- Dosage & Safety: Typical dosages range from 250mg to 1000mg per day. Generally well-tolerated, but always consult your healthcare provider.
Explore our detailed product reviews for NMN here.
Quercetin & Fisetin (Senolytics)
Quercetin and Fisetin are plant flavonoids known for their senolytic properties – meaning they help remove 'senescent' or 'zombie' cells that accumulate with age and contribute to inflammation and disease.
- What they do: Target and clear senescent cells, reducing chronic inflammation and potentially improving tissue function.
- Science Says: Pre-clinical and some human studies suggest benefits for cardiovascular health, cognitive function, and metabolic health.
- Dosage & Safety: Quercetin often dosed around 500mg-1000mg daily; Fisetin around 100mg-200mg. Best taken in cycles.
Read our in-depth comparisons of senolytic supplements on our product spotlight page.
Always remember that supplementation is a personalized journey. We strongly recommend consulting with a knowledgeable healthcare professional before adding any new supplements to your regimen, especially if you have underlying health conditions or are taking other medications.